Stenting strategy

Stents are meshed wired scaffolds implanted into narrowed arteries to prevent heart attacks and strokes. They still fail in 1 in 10 patients besides being the most common treatment for the largest cause of death worldwide. 

The aim of this work is to generate CAD models from micro-CT images of stented patient replicas. The replicas represent the anatomical/geometric distribution found within a large population. The CAD models will be used to generate CFD simulations of the blood flow, revealing their effectiveness for that patient geometry.   

The outcomes are new insights into individual differences opening the pathway to a personalised stenting approach for higher treatment success. 

coronary artery research using benchtop stent work with stents and 3D printed phantoms

Selected publications

  • Ormiston JO; Kassab GK; Finet GF; Chatzizisis YSC; Foin NF; Mickley TJM; Chiastra CC; Murasato YM; Hikichi TH; Wentzel JJW; Darremont OD; Iwasaki IK; Lefevre TL; Louvard YL; Beier S; Hojeibane HH; Netravali AN; Wooton JW; Cowan BC; Webster MIW; Medrano PM; Stankovic GS, 2017, Bench Testing and Coronary Artery Bifurcations: A Consensus Document from the European Bifurcation Club., Eurointervention, vol. 13, pp. e1794 - e1803, http://dx.doi.org/10.4244/EIJ-D-17-00270

  • Masoud-Ansari S; Ormiston J; Webster M; Pontre B; Cowan B; Beier S, 2019, Towards validating stent induced microflow patterns in left main coronary artery bifurcations, in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, pp. 5749 - 5752, http://dx.doi.org/10.1109/EMBC.2019.8856419